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Repolarisation interval and T-wave

Spatial distribution of repolarisation interval and T-wave amplitude were examined using multichannel magnetocardiograms (MCGs), which non-invasively measure variations in magnetic field strength at the body surface.

MCGs were obtained using the PTB multichannel SQUID system at 49 sites over the heart from 8 healthy volunteers. Each recording channel was displayed on a computer screen. Repolarisation intervals and T-wave amplitudes in each channel were measured manually and displayed graphically as contour maps. The Pearson correlation was used to determine the spatial relationship between the two variables.

Mean (SD) values of repolarisation interval and T-wave amplitude equalled 381(7) ms and 4(2) pT respectively. The standard deviation of the difference between repeat measurements for repolarisation interval and T-wave amplitude was 5.2 ms and 0.4 pT respectively. Repolarisation measurements tended to increase by approximately 8 ms for a doubling of T wave height. Contour maps showed two distinct regions of high repolarisation interval (_ 380 ms), corresponding spatially to concentrated areas of high absolute T-wave amplitude (_ 4 pT). A Pearson correlation coefficient of 0.7 (p _ 0.0005) was obtained from this analysis.

Repolarisation intervals and T-wave heights in normal subjects recorded from magnetocardiography have distinctive but related spatial distributions

Publication

Smith FE, Langley P, Steinhoff U, Trahms L, Bourke JP, Murray A. Relation between spatial properties of repolarisation interval and T-wave amplitude using magnetocardiography. Computers in Cardiology 2001;28:629-32.

Contact

Dr. Philip Langley Freeman Unit, Newcastle upon Tyne. Tel: +44 (0)191-223-1370.

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