The aim of this study was to investigate the value of fractal dimension in separating normal and cancerous images, and to examine the relationship between fractal dimension and traditional texture analysis features. Forty-four normal images and 58 cancer images from sections of the colon were analyzed. A "leave-one-out" analysis approach was used to classify the samples into each group. With fractal analysis there was a highly significant difference between groups (p < 0.0001). Correlation and entropy features showed greater differences between the groups (p < 0.0001). Nevertheless, the addition of fractal analysis to the feature analysis improved the sensitivity from 90% to 95% and specificity from 86% to 93%.
Esgiar AN, Naguib RNG, Sharif BS, Bennett MK, Murray A. Fractal analysis in the detection of colonic cancer images. IEEE Trans Info Technol Biomed 2002; 6: 54-8.
Professor Alan Murray, Freeman Unit, Newcastle upon Tyne. Tel: +44 (0)191-223-1370.
Regional Medical Physics Department, Freeman Hospital, Newcastle upon Tyne, NE7 7DN, UK.
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